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HECW1 Polyclonal Antibody, 50ul Antibodies Myosins are actin-dependent motor proteins

SKU: 61289660445

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USD162.00 USD212.00

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HECW1 Polyclonal Antibody, 50ul Antibodies Myosins are actin-dependent motor proteinsE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW

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Description

Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains

PTM:N- and O-glycosylated

This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development

are less active or functional

This gene is found within an intron of another gene| bladder cancer associated protein| but on the opposite strand

HECW1 Polyclonal Antibody, 50ul Antibodies Myosins are actin-dependent motor proteinsE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW

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