TIG1 Polyclonal Antibody, 50ul[BT-AP14966] Buffers & Solutions |Component of the 9-1-1 cell-cycle

|Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair

The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin

a severe mitochondrial encephalomyopathy

The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system

The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily

TIG1 Polyclonal Antibody, 50ul[BT-AP14966] Buffers & Solutions |Component of the 9-1-1 cell-cycleThis gene was identified as a retinoid acid (RA) receptor responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.