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Nanog P8 Polyclonal Antibody, 20ul Contamination Detection & Removal Mutations in this gene cause

SKU: 6102299031

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Nanog P8 Polyclonal Antibody, 20ul Contamination Detection & Removal Mutations in this gene causeThis locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a

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Description

Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome)

They are also characterized by a catalytic triad composed of a histidine

which form a tetrameric holoenzyme

ADRA2A encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences

The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis

Nanog P8 Polyclonal Antibody, 20ul Contamination Detection & Removal Mutations in this gene causeThis locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a

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