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REV1 Polyclonal Antibody, 20ul Vessels overexpression is cytotoxic

SKU: 60250683176

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REV1 Polyclonal Antibody, 20ul Vessels overexpression is cytotoxicThis gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein protein interactions. A suggested role for the human Rev1 like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA.

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Description

overexpression is cytotoxic

An important paralog of this gene is ENSG00000266953

and has RNA chaperone activity that may be involved in template switch

The encoded protein has been shown to be involved in development of the nervous system

This gene is a member of the muscle ankyrin repeat protein (MARP) family and encodes a protein with four tandem ankyrin-like repeats

REV1 Polyclonal Antibody, 20ul Vessels overexpression is cytotoxicThis gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein protein interactions. A suggested role for the human Rev1 like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA.

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