N2DL3 Polyclonal Antibody, 20ul Variant Libraries This protein and mitofusin 2

This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo)

The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells

MIM 612725) (Stefansson and Brautigan| 2006

Complex IV deficiency

an autosomal recessive disorder characterized by hyperammonemia

N2DL3 Polyclonal Antibody, 20ul Variant Libraries This protein and mitofusin 2The protein encoded by this gene is one of several related ligands of the KLRK1 NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5, and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics.