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RFC2 Polyclonal Antibody, 100ul Polyclonal Antibody Preparation Irreversible reprogramming of melanomas can

SKU: 60144309941

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SEK123.75 SEK144.75

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RFC2 Polyclonal Antibody, 100ul Polyclonal Antibody Preparation Irreversible reprogramming of melanomas canRFC2 encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. RFC2 encodes the 40 kD subunit, which has been shown to be responsible for binding ATP

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Description

Irreversible reprogramming of melanomas can be achieved by treatment with both these agents

Different length transcripts presumably resulting from use of alternative polyadenylation site

The encoded protein contains four N-terminal tetratricopeptide domains and a C-terminal Src homology 3 domain

The protein encoded by this gene binds to calmodulin and is expressed in the centrosome

GPR42 appears to have arisen by tandem duplication of FFAR3 and have lost the ability to activate G-protein family in respose to carboxylate ligands primarily due to an amino acid change at position 174

RFC2 Polyclonal Antibody, 100ul Polyclonal Antibody Preparation Irreversible reprogramming of melanomas canRFC2 encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. RFC2 encodes the 40 kD subunit, which has been shown to be responsible for binding ATP

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