Maf1 Polyclonal Antibody, 100ul Cell Transfection Mutations in OCRL cause oculocerebrorenal

Mutations in OCRL cause oculocerebrorenal syndrome of Lowe and also Dent disease

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Interacts with KRT17 (By similarity)

Candidate gene encoding tumor antigens

which is present in many genes with transformation potential

Maf1 Polyclonal Antibody, 100ul Cell Transfection Mutations in OCRL cause oculocerebrorenalMAF1 (MAF1 homolog, negative regulator of RNA polymerase III) encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1 dependent repression.