IFN- gammaR alpha(Phospho Tyr457) Polyclonal Antibody, 50ul Purification This gene is a protooncogene

This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes

This protein has only little activity of internalizing modified low density lipoproteins (LDL)

Forms ternary complex with RTN4R/NGFR and RTN4R/TNFRSF19

and acts as a tumor suppressor in esophageal cancer

Does not activate JNK1/MAPK8 pathway

IFN- gammaR alpha(Phospho Tyr457) Polyclonal Antibody, 50ul Purification This gene is a protooncogeneThis gene (IFNGR1) encodes the ligand binding chain (alpha) of the gamma interferon receptor. Human interferon gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.