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Abl1 Polyclonal Antibody, 50ul[BT-AP00132] Microplate Mixer Homotetramers consisting of a proteolytically

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Abl1 Polyclonal Antibody, 50ul[BT-AP00132] Microplate Mixer Homotetramers consisting of a proteolyticallyABL1 is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein (ABL proto oncogene 1, non receptor tyrosine kinase)is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is

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Description

Homotetramers consisting of a proteolytically cleaved form of the protein| or type A subunit| exhibit low affinity for heparin and do not interact with the ECM

Mutations in this gene are a cause of hypomyelinating leukodystrophy

PTM:Phosphorylated by LYN

in some cases accompanied by neurological abnormalities

Fusion of ATF1 and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma

Abl1 Polyclonal Antibody, 50ul[BT-AP00132] Microplate Mixer Homotetramers consisting of a proteolyticallyABL1 is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein (ABL proto oncogene 1, non receptor tyrosine kinase)is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is

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