Phospho-BLNK (Y96) Polyclonal Antibody, 50ul Cell Biology involved in late-phase long-term potentiation

involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses

It has an altered intracellular processing and is trapped within the endoplasmic reticulum

This protein is not restricted to leukemic cells

Reversibly binds calcium

thereby playing a role in cell migration and growth

Phospho-BLNK (Y96) Polyclonal Antibody, 50ul Cell Biology involved in late-phase long-term potentiationBLNK encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. B cell linker bridges B cell receptor associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia