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TRI63 Polyclonal Antibody, 20ul Lentiviral Packaging DM plays a central role

SKU: 59034532254

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TRI63 Polyclonal Antibody, 20ul Lentiviral Packaging DM plays a central roleThis gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z line and M line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle type creatine kinase.

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Description

DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site

The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops

making it ideal for demanding laboratory applications

This gene encodes a single-pass transmembrane protein

This receptor has been also shown to activate NF-kappaB

TRI63 Polyclonal Antibody, 20ul Lentiviral Packaging DM plays a central roleThis gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z line and M line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle type creatine kinase.

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