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PAI-1 Polyclonal Antibody, 20ul Site-directed Mutagenesis BCAS2 is a transcriptional cofactor

SKU: 58513986000

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PAI-1 Polyclonal Antibody, 20ul Site-directed Mutagenesis BCAS2 is a transcriptional cofactorSERPINE1 encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in SERPINE1 are the cause of plasminogen activator inhibitor 1 deficiency (PAI 1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding

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Description

BCAS2 is a transcriptional cofactor that enhances estrogen receptor-mediated gene expression

where they appear to provide protective functions

Sequence-specific DNA-binding factor that binds to the 5-AGGTCTC-3 sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity)

which are characterized by an N-terminal extracellular mucin domain

Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p

PAI-1 Polyclonal Antibody, 20ul Site-directed Mutagenesis BCAS2 is a transcriptional cofactorSERPINE1 encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in SERPINE1 are the cause of plasminogen activator inhibitor 1 deficiency (PAI 1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding

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