IGF2R(Phospho-Ser2484) Polyclonal Antibody, 50ul Antibody Humanization epigenetic silencing of SFRP genes

epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer

The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA

DNA replication and chromosomal stability

also known as Spondin-2 and DIL-1 (Differentially expressed in cancerous and non-cancerous lung cells 1) belongs to the F-spondin family of secreted extracellular matrix proteins

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IGF2R(Phospho-Ser2484) Polyclonal Antibody, 50ul Antibody Humanization epigenetic silencing of SFRP genesThis gene encodes a receptor for both insulin like growth factor 2 and mannose 6 phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions including in the intracellular trafficking of lysosomal enzymes the activation of transforming growth factor beta and the degradation of insulin like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with