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IRS-1 Polyclonal Antibody, 100ul[BT-AP04645] Lysosome Knockout studies in mice suggest

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IRS-1 Polyclonal Antibody, 100ul[BT-AP04645] Lysosome Knockout studies in mice suggestIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

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Description

Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system

This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity

It is associated with CREM and confers a powerful transcriptional activation function

The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins

MAP4K1 is a Protein Coding gene

IRS-1 Polyclonal Antibody, 100ul[BT-AP04645] Lysosome Knockout studies in mice suggestIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

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