TR beta 1(Phospho Ser142) Polyclonal Antibody, 50ul Human Genome Knockout Libraries Alternative splicing results in two

Alternative splicing results in two transcript variants encoding the same protein

The encoded protein is predominantly localized to the cytoplasm

The encoded protein

As compared to cathepsin B| cathepsin L exhibits higher activity toward protein substrates| but has little activity on Z-Arg-Arg-NHMec| and no peptidyl-dipeptidase activity

This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13

TR beta 1(Phospho Ser142) Polyclonal Antibody, 50ul Human Genome Knockout Libraries Alternative splicing results in twoThe protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone