RGMC Polyclonal Antibody, 50ul Endonucleases & Exonucleases The encoded protein (ADAM metallopeptidase
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RGMC Polyclonal Antibody, 50ul Endonucleases & Exonucleases The encoded protein (ADAM metallopeptidaseThe product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Two uORFs in the 5' UTR negatively regulate the expression and activity of the encoded protein. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in
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