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DBC-1 Polyclonal Antibody, 50ul Cell Separation and Collection This protein is a major

SKU: 57964521074

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DBC-1 Polyclonal Antibody, 50ul Cell Separation and Collection This protein is a majorCore component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T) rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53 TP53

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Description

This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens

Multiple pseudogenes of this gene have been identified

Potassium-transporting ATPase alpha chain 2 encoded by ATP12A belongs to the family of P-type cation transport ATPases

and PRF1 genes

This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA

DBC-1 Polyclonal Antibody, 50ul Cell Separation and Collection This protein is a majorCore component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T) rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53 TP53

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