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Phospho-Akt (S124) Polyclonal Antibody, 50ul Custom RNA Oligos The encoded protein may be

SKU: 57938630601

4.1
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Phospho-Akt (S124) Polyclonal Antibody, 50ul Custom RNA Oligos The encoded protein may beThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329)

It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies

4 - and 5-kb transcripts

containing at least eight independent

eotaxin-3 (CCL26)

Phospho-Akt (S124) Polyclonal Antibody, 50ul Custom RNA Oligos The encoded protein may beThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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