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NR1H2 Polyclonal Antibody, 20ul Nucleic Acid Amplification and oncogenic transformation

SKU: 57921724851

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NR1H2 Polyclonal Antibody, 20ul Nucleic Acid Amplification and oncogenic transformationThe liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand activated LXRs form obligate heterodimers

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Description

and oncogenic transformation

and insulin sensitivity

The activity of this receptor is mediated by G proteins

and that binding is enhanced when cytokeratins 8 and 18 are present

A wide range of enzymes facilitate the proteolytic Ub pathway

NR1H2 Polyclonal Antibody, 20ul Nucleic Acid Amplification and oncogenic transformationThe liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand activated LXRs form obligate heterodimers

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