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LWS Polyclonal Antibody, 50ul Drying & Desiccation Multiple alternatively spliced transcript variants

SKU: 57414162664

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LWS Polyclonal Antibody, 50ul Drying & Desiccation Multiple alternatively spliced transcript variantsThis gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non small cell lung cancer cells.

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Description

Multiple alternatively spliced transcript variants were described| but the full-length sequence of only some were determined

This gene encodes a lysosomal protein that interacts with RAB7

CRHR1 encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway

An important paralog of this gene is SNRNP200

PTX3 encodes a member of the pentraxin protein family

LWS Polyclonal Antibody, 50ul Drying & Desiccation Multiple alternatively spliced transcript variantsThis gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non small cell lung cancer cells.

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