Nibrin(Phospho Ser343) Polyclonal Antibody, 20ul Buffers & Solutions This gene product shows selectivity

This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus

|PTM:Phosphorylated by MAPK1 in response to antigen receptor activation

Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor

This encoded protein is characterized by two WW domains

thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery

Nibrin(Phospho Ser343) Polyclonal Antibody, 20ul Buffers & Solutions This gene product shows selectivityMutations in this gene are associated with Nijmegen breakage syndrome an autosomal recessive chromosomal instability syndrome characterized by microcephaly growth retardation immunodeficiency and cancer predisposition. The encoded protein is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint