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GCK/GLK Polyclonal Antibody, 20ul Erlenmeyer Flasks this gene is disrupted in

SKU: 57393400451

4.1
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GCK/GLK Polyclonal Antibody, 20ul Erlenmeyer Flasks this gene is disrupted inThe protein encoded by this gene is a member of the serine threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B cell differentiation. This kinase can be activated by TNF alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor associated factor 2

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Description

this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion

some of which are disease-associated mutations

Expression of this gene may be regulated by the cytokine TNF-alpha

This gene encodes a beta tubulin protein

It does not have a mouse homolog

GCK/GLK Polyclonal Antibody, 20ul Erlenmeyer Flasks this gene is disrupted inThe protein encoded by this gene is a member of the serine threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B cell differentiation. This kinase can be activated by TNF alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor associated factor 2

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