SQSTM1/p62 Rabbit Polyclonal Antibody, 20ul Reagent Reservoirs These enzymes are thought to
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SQSTM1/p62 Rabbit Polyclonal Antibody, 20ul Reagent Reservoirs These enzymes are thought toThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in
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