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HEXI2 Polyclonal Antibody, 100ul Micro Centrifuge Tubes TNK2 encodes a tyrosine kinase

SKU: 57060216932

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HEXI2 Polyclonal Antibody, 100ul Micro Centrifuge Tubes TNK2 encodes a tyrosine kinaseThis gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin dependent kinase P TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing

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Description

TNK2 encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs

with the highest level of expression in the testes

subunit:Heterodimer of CALCRL and RAMP1

Multiple alternatively spliced transcript variants for RSU1 have been reported

which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein

HEXI2 Polyclonal Antibody, 100ul Micro Centrifuge Tubes TNK2 encodes a tyrosine kinaseThis gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin dependent kinase P TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing

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