TIF1 Alpha Polyclonal Antibody, 50ul Cellular Function Assays The protein encoded by this

The protein encoded by this gene is an autophagy factor and a target of the TOR kinase signaling pathway

The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1

The products of target genes it activates are required for differentitation and mitogenesis

F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes| called SCF complexes| which function in phosphorylation-dependent ubiquitination

|PTM:Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4

TIF1 Alpha Polyclonal Antibody, 50ul Cellular Function Assays The protein encoded by thisTranscription intermediary factor 1 alpha encoded by TRIM24 mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif