Luciferase mouse Monoclonal Antibody(9D6), 20ul Petri Dishes Members of the SOX family

Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain

and associated signaling proteins

Members of this gene family typically encode proteins that contain a paired box domain

Retinoic acid plays a critical role in development

Some individuals with the poor metabolizer phenotype have no functional protein since they carry 2 null alleles whereas in other individuals the gene is absent

Luciferase mouse Monoclonal Antibody(9D6), 20ul Petri Dishes Members of the SOX familyLuciferase from the firefly has become one of the more widely used reporter proteins for the study of gene expression. Luciferase catalyzes a bioluminescent reaction which requires the substrate luciferin as well as Mg2+ and ATP. Mixing these reagents with the cell extract containing luciferase, results in a flash of light that decays rapidly. This light can be detected by a luminometer. The total light emission is proportional to the luciferase