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Phospho-Bim (S59) Polyclonal Antibody, 100ul In vitro Transcription type 5 (HSAN5)

SKU: 56019800301

4.6
USD141.00 USD189.00

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Phospho-Bim (S59) Polyclonal Antibody, 100ul In vitro Transcription type 5 (HSAN5)Bim Bod is a pro apoptotic protein belonging to the BH3 only group of Bcl 2 family members including Bad, Bid, Bik, Hrk, and Noxa that contain a BH3 domain but lack other conserved BH1 or BH2 domains. Bim induces apoptosis by binding to and antagonizing anti apoptotic members of the Bcl 2 family. Interactions have been observed with Bcl 2, Bcl xL, Mcl 1, Bcl w, Bfl 1, and BHRF 1. Bim functions in regulating apoptosis associated with thymocyte negative

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Description

type 5 (HSAN5)

The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain

The protein encoded by this gene belongs to the SAC domain-containing protein gene family

it binds tenaciously to poly(C)

Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells

Phospho-Bim (S59) Polyclonal Antibody, 100ul In vitro Transcription type 5 (HSAN5)Bim Bod is a pro apoptotic protein belonging to the BH3 only group of Bcl 2 family members including Bad, Bid, Bik, Hrk, and Noxa that contain a BH3 domain but lack other conserved BH1 or BH2 domains. Bim induces apoptosis by binding to and antagonizing anti apoptotic members of the Bcl 2 family. Interactions have been observed with Bcl 2, Bcl xL, Mcl 1, Bcl w, Bfl 1, and BHRF 1. Bim functions in regulating apoptosis associated with thymocyte negative

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