IQGAP1 Polyclonal Antibody, 50ul Cell Biology shortness of breath and frequent

shortness of breath and frequent infections

suggesting that this protein may be a potential tumor suppressor

characterized by a zinc finger-like structural motif

tissue specificity:Ubiquitously expressed at low level

disease:Overexpressed and constitutively tyrosine phosphorylated in colon

IQGAP1 Polyclonal Antibody, 50ul Cell Biology shortness of breath and frequentIQGAP1 encodes a member of the IQGAP family. Ras GTPase activating like protein IQGAP1 contains four IQ domains, one calponin homology domain, one Ras GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.