LOXL3 Rabbit Polyclonal Antibody, 50ul Pathway and Network Analysis CLIC6 is part of a

CLIC6 is part of a large triplicated region found on chromosomes 1

The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils

The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases

similarity:Belongs to the protein kinase superfamily

and cysteine carboxypeptidases

LOXL3 Rabbit Polyclonal Antibody, 50ul Pathway and Network Analysis CLIC6 is part of aThis gene encodes a lysyl oxidase which likely functions as an amine oxidase and plays a role in the formation of crosslinks in collagens and elastin. Deletion of the related gene in mouse causes neonatal mortality with cleft palate spine deformity and defects in collagen organization. A mutation in this gene was found in a family with Stickler syndrome.