ET-1 Polyclonal Antibody, 50ul Vacuum Filter The previously defined group FANCH

The previously defined group FANCH is the same as FANCA

GPR116 is a gene on chromosome 6p12

Interleukin-36 beta encoded by IL36B is a member of the interleukin 1 cytokine family

see MIM 608375

Mutations in this gene may be associated with susceptibility to coronary artery disease

ET-1 Polyclonal Antibody, 50ul Vacuum Filter The previously defined group FANCHEDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.