JMY Polyclonal Antibody, 50ul Peptide Modification This gene is located in

This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias

With a specialized treatment

and cryptic domain

Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex

Two related pseudogenes have been identified on chromosome 14

JMY Polyclonal Antibody, 50ul Peptide Modification This gene is located inJMY is a Protein Coding gene. Junction mediating and regulatory protein acts both as a nuclear p53 TP53 cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53 TP53 response via its interaction with p300 EP300. Increases p53 TP53 dependent transcription and apoptosis, suggesting an important role in p53 TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation