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IκB-alpha(Phospho Tyr42) Polyclonal Antibody, 100ul Electrophoresis & Labeling Mutations in this gene are

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IκB-alpha(Phospho Tyr42) Polyclonal Antibody, 100ul Electrophoresis & Labeling Mutations in this gene areThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

Mutations in this gene are associated with osteoarthritis in humans

Mutations in COL5A1 are associated with Ehlers-Danlos syndrome

The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS

Interferon gamma is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections

37 kDa or 320aa

IκB-alpha(Phospho Tyr42) Polyclonal Antibody, 100ul Electrophoresis & Labeling Mutations in this gene areThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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