LKB1(Phospho Ser428) Polyclonal Antibody, 50ul Mechanical Pipette The encoded protein can homodimerize

The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel

which play a role in cytoskeletal formation by regulating actin polymerization

The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II)| which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation

including in thyroid

Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca (2+) handling in myocytes

LKB1(Phospho Ser428) Polyclonal Antibody, 50ul Mechanical Pipette The encoded protein can homodimerizeThis gene, which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not