UBR5 Polyclonal Antibody, 50ul RNA Tools The protein encoded by this

The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes

which facilitates RA binding to its cognate receptor complex and transfer to the nucleus

The protein encoded also exhibits antimicrobial activity against bacteria

There is a pseudogene for this gene on chromosome 12

The precursor of caspase 7 is cleaved by caspase 3 and 10

UBR5 Polyclonal Antibody, 50ul RNA Tools The protein encoded by thisUBR5 encodes a progestin induced protein, which belongs to the HECT (homology to E6 AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin protein ligases, targeting specific proteins for ubiquitin mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.