Rb Polyclonal Antibody, 50ul[BT-AP07685] Peptide Library Fully programmable

Fully programmable

It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins

is a type II membrane glycoprotein that exists as a disulfide-linked homodimer of two identical subunits

and acts as a channel for regulatory signals

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Rb Polyclonal Antibody, 50ul[BT-AP07685] Peptide Library Fully programmableRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.