eIF4B Polyclonal Antibody, 50ul Centrifuges The RING finger and B-box

The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions

Isoform 3 is catalytically inactive

causes vasodilation

subunit:Interacts with FGFR1 and FGFR4

This protein binds to the SH3 domains of GRB2| an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras)| via its C-terminal proline-rich sequences| and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2

eIF4B Polyclonal Antibody, 50ul Centrifuges The RING finger and B-boxRequired for the binding of mRNA to ribosomes. Functions in close association with EIF4 F and EIF4 A. Binds near the 5' terminal cap of mRNA in presence of EIF 4F and ATP. Promotes the ATPase activity and the ATP dependent RNA unwinding activity of both EIF4 A and EIF4 F.