Cytokeratin 18 Monoclonal Antibody(1B3), 50ul PCR Series Binding of insulin to the

Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake

Defects in the gene encoding ZFYVE19 are associated with acute myeloblastic leukemia (AML)

Alternatively spliced transcript variants have been identified in this gene

This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C

The encoded preproprotein is proteolytically processed by furin to generate the mature receptor

Cytokeratin 18 Monoclonal Antibody(1B3), 50ul PCR Series Binding of insulin to theKRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.