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KChIP1 Polyclonal Antibody, 100ul[BT-AP10626] Protein Analysis The protein encoded by this

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KChIP1 Polyclonal Antibody, 100ul[BT-AP10626] Protein Analysis The protein encoded by thisThis gene encodes a member of the family of cytosolic voltage gated potassium (Kv) channel interacting proteins (KCNIPs), which belong to the neuronal calcium sensor (NCS) family of the calcium binding EF hand proteins. They associate with Kv4 alpha subunits to form native Kv4 channel complexes. The encoded protein may regulate rapidly inactivating (A type) currents, and hence neuronal membrane excitability, in response to changes in the concentration

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Description

The protein encoded by this gene contains two doublecortin domains| which bind microtubules and regulate microtubule polymerization

This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues

An important paralog of this gene is BARX2

it is probably inactive as an hydrolase due to lack of the conserved zinc-binding and active sites

Multiple alternatively spliced transcript variants have been found

KChIP1 Polyclonal Antibody, 100ul[BT-AP10626] Protein Analysis The protein encoded by thisThis gene encodes a member of the family of cytosolic voltage gated potassium (Kv) channel interacting proteins (KCNIPs), which belong to the neuronal calcium sensor (NCS) family of the calcium binding EF hand proteins. They associate with Kv4 alpha subunits to form native Kv4 channel complexes. The encoded protein may regulate rapidly inactivating (A type) currents, and hence neuronal membrane excitability, in response to changes in the concentration

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