IPO9 Polyclonal Antibody, 50ul Variant Libraries Putative transcription factor
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IPO9 Polyclonal Antibody, 50ul Variant Libraries Putative transcription factorFunctions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the
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