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Pim-1(Phospho Tyr309) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) The encoded protein is a

SKU: 5268837840

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Pim-1(Phospho Tyr309) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) The encoded protein is aThe protein encoded by this gene belongs to the Ser Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes

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Description

The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells

and it associates maximally with the nucleotide-free states of these GTPases

The ectodomain

PTM:May be proteolytically processed at the boundary between the N-terminal non-conserved and the central conserved domain in neuron-like cells

RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors

Pim-1(Phospho Tyr309) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) The encoded protein is aThe protein encoded by this gene belongs to the Ser Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes

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