MSH3 Polyclonal Antibody, 50ul Molecular Biology 4 volumes available: 0

4 volumes available: 0

This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping

The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor

Gene Ontology (GO) annotations related to SRCIN1 include protein kinase binding and protein domain specific binding

Tie-1 and tek/tie-2 define a new class of RTKs containing two immunoglobulin-like domains

MSH3 Polyclonal Antibody, 50ul Molecular Biology 4 volumes available: 0DNA mismatch repair protein Msh3 encoded by MSH3 forms a heterodimer with MSH2 to form MutS beta, part of the post replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3 7 repeats have been reported.