GEMI8 Polyclonal Antibody, 50ul Purification API5 encodes an apoptosis inhibitory

API5 encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine

Cleaves ubiquitin fusion protein substrates

Paired box transcription factors are important regulators in early development

The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm

GEMI8 Polyclonal Antibody, 50ul Purification API5 encodes an apoptosis inhibitoryThe protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6 GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene.