BLMH Rabbit Polyclonal Antibody, 20ul Miscellaneous Mutations in PAX8 have been

Mutations in PAX8 have been associated with thyroid dysgenesis

It is one of seven related genes or pseudogenes found in a cluster

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The gamma 3 chain is most similar to the gamma 1 chain

Probably involved in a neuron-specific signal transduction

BLMH Rabbit Polyclonal Antibody, 20ul Miscellaneous Mutations in PAX8 have beenBleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.