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Caspase12 Polyclonal Antibody, 50ul miRNA / siRNA Synthesis The encoded protein may play

SKU: 51657764573

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Caspase12 Polyclonal Antibody, 50ul miRNA / siRNA Synthesis The encoded protein may playCaspases are cysteine proteases that cleave C terminal aspartic acid residues on their substrate molecules. CASP12 is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of CASP12 mediates apoptosis in response to endoplasmic reticulum stress. However, in humans CASP12 contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals

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Description

The encoded protein may play a role in spermatogenesis

The protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity| and therefore is known as a dual specificity phosphatase

The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles

Interaction with MUC1 is stimulated by 7 beta-estradiol (E2) and enhances ERS1-mediated transcription

and is involved in translocation with the ets variant 6 gene in leukemia

Caspase12 Polyclonal Antibody, 50ul miRNA / siRNA Synthesis The encoded protein may playCaspases are cysteine proteases that cleave C terminal aspartic acid residues on their substrate molecules. CASP12 is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of CASP12 mediates apoptosis in response to endoplasmic reticulum stress. However, in humans CASP12 contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals

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