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GLI2 Polyclonal Antibody, 100ul In vitro Assessment The protein is a replication-independent

SKU: 51498518932

4.3
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GLI2 Polyclonal Antibody, 100ul In vitro Assessment The protein is a replication-independentThis gene encodes a protein which belongs to the C2H2 type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene

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Description

The protein is a replication-independent histone that is a member of the histone H3 family

Overexpression of this gene may play a role in leukemogenesis| and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein

which is important for the microbicidal activity of these cells

The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions| where they appear to provide protective functions

This protein may tightly associate or interact with the pyruvate dehydrogenase complex

GLI2 Polyclonal Antibody, 100ul In vitro Assessment The protein is a replication-independentThis gene encodes a protein which belongs to the C2H2 type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene

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