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MDMX(Phospho Ser367) Polyclonal Antibody, 20ul Centrifuges Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein

SKU: 51231143752

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SEK111.00 SEK151.00

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MDMX(Phospho Ser367) Polyclonal Antibody, 20ul Centrifuges Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation proteinThis gene encodes a nuclear protein that contains a p53 binding domain at the N terminus and a RING finger domain at the C terminus, and shows structural similarity to p53 binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation

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Description

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide

This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues

Mutations in dysferlin| a protein associated with the plasma membrane| can cause muscle weakness that affects both proximal and distal muscles

Belongs to the CRISP family

MDMX(Phospho Ser367) Polyclonal Antibody, 20ul Centrifuges Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation proteinThis gene encodes a nuclear protein that contains a p53 binding domain at the N terminus and a RING finger domain at the C terminus, and shows structural similarity to p53 binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation

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