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CD327 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation Mutations in this gene are

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CD327 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation Mutations in this gene areThis gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin like lectin) family of proteins. The encoded transmembrane receptor binds sialyl TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia.

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Description

Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D| and expression of this gene may be a prognostic indicator for several types of cancer

FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE

It may instead modulate signal transduction through the beta-arrestin pathway

Alternatively spliced transcript variants encoding multiple isoforms have been observed for PIAS2

they affect cell survival

CD327 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation Mutations in this gene areThis gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin like lectin) family of proteins. The encoded transmembrane receptor binds sialyl TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia.

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