IFN- gammaR alpha(Phospho Tyr457) Polyclonal Antibody, 100ul Multi-Layer Cell Culture System An important paralog of this

An important paralog of this gene is GBP7

a cytosolic phosphoprotein implicated in tumorigenesis

which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules

The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity

The encoded protein may play a role in breast cancer proliferation and chemoresistance

IFN- gammaR alpha(Phospho Tyr457) Polyclonal Antibody, 100ul Multi-Layer Cell Culture System An important paralog of thisThis gene (IFNGR1) encodes the ligand binding chain (alpha) of the gamma interferon receptor. Human interferon gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.