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HUS1B Polyclonal Antibody, 50ul Culture Media Could have a dual role

SKU: 50777132176

4.5
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HUS1B Polyclonal Antibody, 50ul Culture Media Could have a dual roleThe protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.

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Description

Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping

suggesting that this receptor is G(q)-coupled

It associates with protein kinases A and C and phosphatase

NECTIN1 encodes nectin cell adhesion molecule 1 that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells

Mutations in this gene are associated with Nijmegen breakage syndrome| an autosomal recessive chromosomal instability syndrome characterized by microcephaly| growth retardation| immunodeficiency| and cancer predisposition

HUS1B Polyclonal Antibody, 50ul Culture Media Could have a dual roleThe protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.

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