ETBR Polyclonal Antibody, 100ul Drying & Desiccation Single nucleotide polymorphisms in this

Single nucleotide polymorphisms in this gene are associated with Kawasaki disease

This protein is overexpressed in fetal Down syndrome brain

WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD)| which may facilitate formation of heterotrimeric or multiprotein complexes

The protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity| and therefore is known as a dual specificity phosphatase

Naturally occurring read-through transcription occurs between this locus and the neighboring locus HSPE1

ETBR Polyclonal Antibody, 100ul Drying & Desiccation Single nucleotide polymorphisms in thisThe protein encoded by EDNRB (endothelin receptor type B) is a G protein coupled receptor which activates a phosphatidylinositol calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: eT1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding